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Wyświetlanie 1-20 z 33192
Tytuł:
Bogumił Pahl,,Podatki i opłaty lokalne. Teoria i praktyka' Wydawnictwo Wolters Kluwer Polska SA, Warszawa 2017, ISBN 978-83-8107-294-6, ss. 312
Autorzy:
Robert Kwaśniewski
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Temat:
Comparative law. International uniform law
K520-5582
Political institutions and public administration (General)
JF20-2112
Źródło:
Prawo Budżetowe Państwa i Samorządu, Vol 5, Iss 2, Pp 101-119 (2017)
Opis pliku:
electronic resource
Relacje:
http://apcz.umk.pl/czasopisma/index.php/PBPS/article/view/PBPS.2017.012/12537; https://doaj.org/toc/2300-9853; https://doaj.org/toc/2353-7086
Dostęp URL:
https://doaj.org/article/e4a1537f2d0a43d0b2e67f9643adb4f9  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Bogumił Pahl, ,,Podatki i opłaty lokalne. Teoria i praktyka' Wydawnictwo Wolters Kluwer Polska SA, Warszawa 2017, ISBN 978-83-8107-294-6, ss. 312
Autorzy:
Robert Kwaśniewski
Pokaż więcej
Temat:
lcsh:K520-5582
lcsh:Comparative law. International uniform law
lcsh:JF20-2112
lcsh:Political institutions and public administration (General)
Źródło:
Prawo Budżetowe Państwa i Samorządu, Vol 5, Iss 2, Pp 101-119 (2017)
Dostęp URL:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0684aee190c51cb35e3c55fac09fa5  Link otwiera się w nowym oknie
https://doi.org/10.12775/pbps.2017.012  Link otwiera się w nowym oknie
Szczegóły
Tytuł:
Lokalne bieguny wzrostu w Polsce (według budżetów gmin i przedsiębiorczości prywatnej)
Autorzy:
Jerzy Dębski
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Temat:
lokalne
bieguny wzrostu
Polska
budżet
gminy
Industries. Land use. Labor
HD28-9999
Źródło:
Prace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, Vol 5 (2003)
Opis pliku:
electronic resource
Relacje:
https://prace-kgp.up.krakow.pl/article/view/867; https://doaj.org/toc/2080-1653; https://doaj.org/toc/2449-903X
Dostęp URL:
https://doaj.org/article/44c8d05071234a0285677b08f60ec9a6  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Motile sperm organelle morphology evaluation-selected globozoospermic human sperm with an acrosomal bud exhibits novel patterns and higher levels of phospholipase C zeta
Autorzy:
Kashir, J.
Sermondade, N.
Sifer, C.
Oo, S. L.
Jones, C.
Mounce, G.
Turner, K.
Child, T.
McVeigh, E.
Coward, K.
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Temat:
Obstetrics and Gynecology
Rehabilitation
Reproductive Medicine
Źródło:
Human Reproduction ; volume 27, issue 11, page 3150-3160 ; ISSN 0268-1161 1460-2350
Dostępność:
https://doi.org/10.1093/humrep/des312
http://academic.oup.com/humrep/article-pdf/27/11/3150/2436687/des312.pdf
Czasopismo naukowe
Szczegóły
Tytuł:
Figure 16. Model for septin recruitment, ring formation and disassembly. ; (A) Cdc42-GDP recruits septin complexes to the bud site. (B) At the bud site Cdc24 catalyzes the nucleotide exchange of Cdc42, which recruits its effector Gic1. (C) Septins polymerize. (D) Gic1 scaffolds and stabilizes septin filaments and forms septin-Gic1-Cdc42-GTP filament cables that are used for building the septin ring. (E) Cdc42-GTP is not necessary for the stability of the filament cables and upon GTP hydrolysis dissociates from the septin-Gic1 complexes. (F) Cdc42-GDP recruits more septin complexes to the bud site. (G) During cell division the local concentration of Cdc42-GTP increases by the up-regulation of Cdc24. This leads to a dissociation of the septin-Gic1-Cdc42-GTP filament cables and the septin ring disassembles. (H) After Cdc42-GAP catalyzed hydrolysis, Cdc42-GDP binds to the septin filaments and disassembles them to octamers. Septins are depicted as orange rods. Green caps indicate Cdc11. Gic1 is depicted as a blue rectangle. Cdc42-GTP and Cdc42-GDP are depicted as red and yellow rectangles, respectively.
Dostępność:
https://doi.org/10.7554/elife.01085.023
Szczegóły
Tytuł:
Figure 6—figure supplement 2. Morphological integration between the shapes of the limb bud and the Dusp6 gene expression domain, as measured by partial least square (PLS) analysis. ; Results display the morphings associated with the negative, mid and positive values of PLS1 for hindlimbs (A) and forelimbs (B), which accounted for more than 95% of the covariation between the limb buds and the Dusp6 gene expression domains. Separate PLS analyses for hindlimbs (C) and forelimbs (D) for each developmental group, as defined in Table 2 and Figure 4, are also shown. Formal testing of differences in the intensity of the integration patterns in unaffected and Fgfr2+/P253R mutant mice at each stage was not possible because of sample size limitations, as specified in 'Materials and methods' and in Table 2. Individual scores are available in Figure 6—figure supplement 2—source data 1. Rich media.
Dostępność:
https://doi.org/10.7554/elife.36405.023
Szczegóły
Tytuł:
Deletion of meso-2,3-butanediol dehydrogenase gene bud C for enhanced D-2,3-butanediol production in Bacillus licheniformis
Autorzy:
Qi, Gaofu
Kang, Yanfang
Li, Lu
Xiao, Aifang
Zhang, Shumeng
Wen, Zhiyou
Xu, Dihong
Chen, Shouwen
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Temat:
Management, Monitoring, Policy and Law
General Energy
Renewable Energy, Sustainability and the Environment
Applied Microbiology and Biotechnology
Biotechnology
Źródło:
Biotechnology for Biofuels ; volume 7, issue 1 ; ISSN 1754-6834
Dostępność:
https://doi.org/10.1186/1754-6834-7-16
Czasopismo naukowe
Szczegóły
Tytuł:
Figure 6. Quantitative correlation between the size and shape of the limbs and the Dusp6 expression pattern. ; (A–D) Comparison of limb bud size and Dusp6 volume in unaffected and Fgfr2+/P253R mutant littermates across development (Table 3). Limb size was measured as limb centroid size (A), whereas the size of the Dusp6 expression was measured as the volume of the gene domain (B), as specified in the 'Materials and methods' and in Table 2. Statistically significant differences as revealed by two-tailed t-tests are marked with asterisks, representing the degree of significance: *P-value=0.03, **P-value=0.01. Results from hindlimbs and forelimbs are separately available in Figure 6—figure supplement 1. The association between the size of the limbs and the volume of the Dusp6 domain was assessed separately for forelimbs (C) and hindlimbs (D). Individual scores for all of these analyses are available in Figure 6—source data 1. (E) Time course assessing the morphological integration pattern between the limb phenotype and the shape of the gene expression pattern using partial least squares analyses. Associated shape changes from late to early limb development are shown from morphings associated with the negative, mid and positive values of PLS1, which accounted for almost all of the covariation (97.6% in forelimbs and 99.5% in hindlimbs) between the limb buds and the Dusp6 gene expression domains (Figure 6—figure supplement 2). Limb buds and Dusp6 domains are not shown to scale and are oriented distally to the left, proximally to the right, anteriorly to the top and posteriorly to the bottom. On the right, representing the positive extreme of PLS1 axis, typical early limb buds showed a protruding shape (i.e. short in the proximo-distal axis and symmetrical in the antero-posterior axis) associated with a flat-bean shaped Dusp6 expression zone localized in the distal limb region, underlying the apical ectodermal ridge and spreading proximally towards the dorsal and ventral sides of the limb. On the left, representing the negative extreme of the PLS1 axis, limb buds were elongated in the proximal axis and asymmetric on the antero-posterior axis, with an expansion of the distal limb region and a contraction of the proximal region, at the wrist level. This limb shape, which is typical of more developed limbs, was associated with a Dusp6 expression that was extended underneath the apical ectodermal ridge towards the anterior and the posterior ends of the gene expression zone, but reduced on the dorsal and ventral sides of the limb. Individual scores for all of these analyses are available in Figure 6—figure supplement 2—source data 1. Legends for supplementary figures.
Dostępność:
https://doi.org/10.7554/elife.36405.021
Szczegóły
Tytuł:
Figure 6—figure supplement 1. Quantitative size analyses of limb bud and Dusp6 volume in unaffected and Fgfr2+/P253R mutant littermates throughout development. ; Comparison in hindlimbs (A, C) and forelimbs (B, D) at each developmental period, as defined in Table 2 and Figure 4. Limb size was measured in terms of limb centroid size (μm), whereas the size of the Dusp6 expression zone was measured as the volume of the gene expression domain (μm3). Statistical significant differences as revealed by two-tailed t-tests are marked with asterisks: *P-value
Dostępność:
https://doi.org/10.7554/elife.36405.022
Szczegóły
Tytuł:
Figure 1. Bmp7R-GFlag homozygotes show earlier lethality and more severe phenotypic defects than Bmp7 null homozygotes. ; (A) Illustration of two hypothetical models in which class I and II BMPs function predominantly as homodimers (top) or as heterodimers (bottom) within select cell types. In the heterodimer model, class I/II heterodimers form preferentially. In addition, it is hypothesized that there is an excess of class II BMPs that form homodimers in the wild type condition but are available to form heterodimers to compensate for loss of any single class II BMP. (B) Illustration of BMP7R-GFlag precursor protein forming homodimers (top) or heterodimers with BMP2 or BMP4 (bottom). Prodomain: dark shading, mature domain: light shading, black bar: FLAG epitope. (C) Illustration showing predicted loss of BMP activity in Bmp7R-GFlag or Bmp7 null homozygotes if BMPs function predominantly as homodimers (top) or as heterodimers (bottom). In cells in which only homodimers form, there is predicted to be an equivalent reduction in BMP activity in Bmp7-/- and in Bmp7R-GFlag/Flag mice because only BMP7 homodimers are absent or inactive (black X), respectively. In cells or tissues in which class I/II heterodimers are the primary functional ligand, excess class II molecules that normally form homodimers will fill in to maintain the heterodimer pool in Bmp7 null mutants (lower left), but cannot do so in Bmp7R-GFlag mutants because the BMP7R-GFlag precursor protein forms non-functional covalent heterodimers with endogenous class I BMPs (lower right). This would lead to a greater reduction in the heterodimer pool, lower total BMP activity and more severe phenotypic defects in Bmp7R-GFlag than in then Bmp7 null mutants in any tissues or cell types where heterodimers predominate. (D–L’) Photograph of E9.5–11.5 (age indicated to left of each row) wild type (D–L) or mutant (D’-L’; genotype listed at top of each column) littermates. Scale bars in Panel F’, I’ and L’ correspond to 1 mm and apply across each row. A minimum of eight embryos of each genotype were analyzed at each stage. Arrows in H’ indicate pericardial edema. fb; forebrain, mb; midbrain, hb; hindbrain, flb; forelimb bud, e; eye.
Dostępność:
https://doi.org/10.7554/elife.48872.002
Szczegóły
Tytuł:
Figure 3. Pharmacological modulation of β-catenin signalling alters distal segment development. ; (A) Lgr5-EGFP expression in treated nephrons with segmentation markers. (B) Time-lapse analysis of treated Lgr5+/EGFP-IRES-CreERT2 kidneys–arrowheads indicate developing nephrons, red-dashed line indicates ureteric bud (UB). (C) Mean number of Lgr5-EGFP positive nephrons per kidney.
Dostępność:
https://doi.org/10.7554/elife.04000.005
Szczegóły
Wyświetlanie 1-20 z 33192

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